甲苯磺酸利特昔替尼胶裹Ritlecitinib Tosylate 50mg

Litrextoinib is a kinase inhibitor indicated for the treatment of adolescents aged 12 years and older and adults with severe alopecia areata. Use Restriction: Concomitant use with other Janus kinase (JAK) inhibitors, biological immunomodulators, cyclosporine, or other potent immunosuppressants is not recommended.

The recommended dose of this product is 50 mg once daily, for oral administration, with or without food. Swallow the capsules whole. Do not crush, cut or chew them. If a dose is missed, take the missed dose as soon as possible. However, if the interval before the next scheduled dose is less than 8 hours, the missed dose should not be taken. After that, continue taking the medication according to the regular schedule. No dose adjustment is required for patients with mild (Child-Pugh Class A) or moderate (Child-Pugh Class B) hepatic impairment. Use of litrextoinib is not recommended for patients with severe (Child-Pugh Class C) hepatic impairment.

Avoid using litrextoinib in patients with active, severe infections. During and after administration of litrextoinib, closely monitor patients for signs and symptoms of infection. Initiation of litrextoinib treatment is not recommended in patients with active tuberculosis (TB). If a patient develops herpes zoster, consider interrupting treatment until resolution. For patients with a known malignancy (except for cured non-melanoma skin cancer (NMSC) or cervical cancer), the risks and benefits of treatment should be considered before initiating or continuing litrextoinib therapy. Exercise caution when using litrextoinib in patients with known risk factors for thromboembolism. Discontinue litrextoinib and initiate appropriate treatment if a clinically significant hypersensitivity reaction occurs. If a patient develops central auditory impairment during medication, discontinue litrextoinib until the cause is identified. Exercise caution when administering this product to pregnant women, children and elderly patients.

Headache, diarrhea, acne, rash, urticaria, folliculitis, fever, atopic dermatitis, dizziness, elevated blood creatine phosphokinase, herpes zoster, decreased red blood cell count, oral mucositis, etc.

28 capsules per bottle.

Store in a sealed container, below 30℃. Keep out of the reach of children.